A1 is an interneuron in Pleurobranchaea
NeuronBank Accession ID: Ple0002601
- Coloration: White
- Location: The larger, more anterolateral of the two white cells in the A cluster of the of the cerebral ganglion.
- size: 50 -110 microns in animals 10 - 600 gm - slightly larger than nearby neurons
- Axon Projection: Contralateral through cerebral commissure, then through anterior cerebropedal connective to pedal ganglion, then through pedal commissure
- Resting Membrane Potential: -48.6 mV
- Spike Height: 70.3 mV
- Excited by sensory afferents - no indication of whether this is mono or polysynaptic
- Electrically coupled to A3 and inhibited by A3
- Polysynaptic inhibition of Phasic Paracerebral Neuron (PCp)
- A1 is a member of the swim CPG circuit. It is rhythmically active during the swim motor pattern and can reset the motor pattern.
- A1 stimulation inhibits feeding.
- Stimulation of A1 in non-swimming whole-animal preparation has a biphasic effect:
- The animal straightens like a dorsal flexion
- The animal turns to the side contralateral to the A1 soma being stimulated.
- J. Jing and R. Gillette. Neuronal elements that mediate escape swimming and suppress feeding behavior in the predatory sea slug Pleurobranchaea. J.Neurophysiol. 74 (5):1900-1910, 1995.PMID:8592183
- J. Jing and R. Gillette. Central pattern generator for escape swimming in the notaspid sea slug Pleurobranchaea californica. J.Neurophysiol. 81 (2):654-667, 1999. PMID:10036268